Zeolites role in prevention or treatment of some animal diseases

Studies have shown that natural and synthetic zeolites, in addition to its role in improving animal performance, to prevent the toxicity of ammonia, heavy metals and radioactive elements and in reducing metabolic skeletal defects are effective. Consumed zeolites by the animal participate in many biochemical processes through ion exchange, adsorption and catalytic.
In following the effect of zeolites on some farm animals diseases will bw discussed and proposed mechanisms of these effects are briefly described. Reducing effects of mycotoxicos: In recent years, grain and animals food contamination with mycotoxins widely has been reported.
One of the newest ways to reduce these pollutions in the world is the usage of sorbent feed in diets which binds mycotoxins and reduce their absorption from intestine and prevents toxic compounds transition to livestock and their products. Preventive effect of diarrhea syndrome: There are many published studies that demonstrate the usage of natural zeolites in the diet decreased the incidence, severity and duration of diarrhea in calves and pigs.
The exact mechanism of this effect has not been understood properly, but there is evidences that the usage of zeolites eliminate several factors that cause and predispose digestive disorders. Poisoning by heavy metals and radioactive uptake: zeolites because of their highly capacity of ion exchange are effective for the prevention of heavy metal toxicity in animals.
Pound and colleagues (1983) found that rats which fed with Clinoptilolite would be protected against lead toxicity when the ration of lead to Clinoptilolite is 10 to 1. Reduction in parasitic infections: According to the tests results on rats and zeolites impact potential on parasitic infections, their usage in other animal species were considered as well.
According to the findings of Wales and Mac Howe (1983) Using of 10% Clinoptilolite in diet of rats with Nippostrongylus brasiliensis nematode accelerate the removal of intestinal parasite. So Wales Vakidof (1985) observed faster recovery of mice intestinal enzyme of alpha-D Glycosides and amino pitidaz that were fed with a diet of 5% Clinoptilolite and get rid of N. brasiliensis infection.
Possible interactions with drugs: In fact the property of non-specific adsorption and cationic exchange capacity of the zeolites could be causes the risks associated with the availability of drugs used in the field pharmaceutical plan which increase performance and maintain the health of the animals. Rodriguez et al. (1997) studied the disrupt ability of a natural zeolite on the antibacterial effect of tetracycline and choloramphicol which was used in prophylactic minimum values.
The simultaneous presence of enriched zeolite with Hyvandyt Clinoptilolite and antimicrobial in culture environment, does not increase the total amount of bacteria growth prevention. However, from the perspective of clinical and pharmacology no clear interaction is not verified between zeolite and certain medications to maintain animal health status. In contrast, recent work suggests that zeolites because of buffering the gut contents while passing through the different parts of the gastrointestinal tract could be used to enhance bioavailability of known drugs.

By Dr. Maziar Mohiti Asli, Poultry Nutritionist
DGM-Technomix Scientific Group
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